NEUTRALIZATION OF VIRUSES BY HOMOLOGOUS IMMUNE SERUM
نویسندگان
چکیده
منابع مشابه
Neutralization of Viruses by Homologous Immune Serum
On the assumption that antibody is added to virus particles in a stepwise manner and that the reaction follows the law of mass action, a theoretical equation for the equilibrium state of virus neutralization reactions has been deduced. The theory has been found to be in reasonable accord with the available data for the neutralization of bacterial viruses and can be applied also to data for the ...
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Antigenic variants of influenza A virus strains emerge on serial passage in ovo in the presence of immune serum against different but related strains. An old laboratory strain (PR8) which had been through hundreds of animal passages was as readily modified by this procedure as recently recovered strains. Such variants apparently can be obtained at will and show antigenic patterns which are repr...
متن کاملThe Recovery of Vaccine Virus after Neutralization with Immune Serum
1. When vaccine virus and its specific antiserum are brought together, no evidence of stable union between them can be determined by the experimental methods employed. 2. A definite relationship exists between the degree of dilution of a neutral vaccine virus-antiserum mixture and the size of the lesion produced by endermic inoculation of rabbits of any given dilution.
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Under natural conditions, reactions between viruses and antibodies occur in living host tissues. Because of the importance of such reactions in immunity to virus infections, much attention has been directed toward them. The most nearly natural model which is available for detailed study in the laboratory appears to be the reaction in which the infectivity of a virus is neutralized by homologous...
متن کاملTHE ANTIGENICITY OF d-RIBONUCLEASE; THE INHIBITION OF THE ENZYME BY ITS HOMOLOGOUS IMMUNE SERUM
The enzyme d-ribonuclease is antigenic. Antisera, prepared by three different methods, reacted against antigen dilutions up to one million. Apparently the homologous antiserum, when combined with the d-ribonuclease inhibited the activity of the enzyme from 10 to 30 per cent.
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1953
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.97.6.845